PUMA antibody (AA 186-199)

Catalog No. ABIN208703

The Rabbit Polyclonal anti-PUMA antibody has been validated for WB, IHC and IHC (p). It is suitable to detect PUMA in samples from Human.

Quick Overview for PUMA antibody (AA 186-199) (ABIN208703)

Target: PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUMA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PUMA Antibody

Binding Specificity: AA 186-199

Specificity: The amino acid sequence used as immunogen is 100 % homologous in human (PUMA a and b) and 78 % homologous in mouse and rat. Human PUMA a is a 193 amino acid protein with a predicted molecular weight of approximately 22 kD. Human PUMA b is a 131 amino acid protein with a predicted molecular weight of approximately 15 kD.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gibbon (100%) Marmoset (93%) Panda, Horse, Pig (86%).

Purification: Protein G purified

Immunogen: A portion of amino acids 186-199 (PLPRGHRAPEMEPN ) of human PUMA a. Percent identity by BLAST analysis: Human, Monkey (100%), Marmoset (93%), Ferret, Panda, Dog, Horse, Pig (86%), Mouse, Rat (79%).

Type of Immunogen: Protein fragment

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P, WB (1:500 - 1:1000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Short term: 4°C
Long term: -70°C.

Target Details for PUMA

Target: PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Alternative Name: PUMA

Background: Name/Gene ID: BBC3
Family: Apoptosis

Synonyms: BBC3, Bcl-2-binding component 3, BCL2 binding component 3, JFY-1, JFY1, PUMA

Gene ID: 27113

UniProt: Q9BXH1

Pathways: p53 Signaling, Positive Regulation of Endopeptidase Activity