MTOR antibody (pSer2448)

Catalog No. ABIN2140768

This Rabbit Polyclonal antibody specifically detects MTOR in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for MTOR antibody (pSer2448) (ABIN2140768)

Target: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTOR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MTOR Antibody

Binding Specificity: pSer2448

Purification: mTOR antibody was purified by immunoaffinity chromatography.

Immunogen: mTOR antibody was raised in Rabbit using the peptide sequence around phosphorylation site of Ser2448 (T-D-S(p)-Y-S) derived from Human mTOR as the immunogen.

Application Details

Application Notes: IF: 1:100-1:200, IHC: 1:50-1:100, WB: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: In liquid form PBS buffer (no MG2+ or Ca2+), pH 7.4, 150 mm NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles

Storage: -20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for MTOR

Target: MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))

Alternative Name: mTOR

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect