Lamin A/C antibody

Catalog No. ABIN215965

This Mouse Monoclonal antibody specifically detects Lamin A/C in WB, IHC, IF and IHC (fro). It exhibits reactivity toward Human, Mouse, Rat, Cow and Xenopus laevis.

Quick Overview for Lamin A/C antibody (ABIN215965)

Target: Lamin A/C (LMNA)

Reactivity: Human, Mouse, Rat, Cow, Xenopus laevis

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lamin A/C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Lamin A/C Antibody

Specificity: Decorates the karyoskeleton, i. e. the intermediate filament equivalent of the nucleus. Polypeptide (s) Reacting: Lamin isotypes of Mr 60-75kD. Species cross-reactivity: Xenopus laevis LII, LIII Bovine LB1, B2 Mouse LB2 Rat + Human LB1, B2 Trout LII, LIII Rat kangaroo LII, LIII.

Purification: Protein A purified

Immunogen: Nuclear pore complex-lamina fraction of Xenopus laevis (XLKE-A6 cells).

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: IF, IHC (1:10), IHC-Fr, WB

Usage: Suitable for use in Immunofluorescence microscopy, Immunohistochemistry and Western Blot (Western). Immunohistochemistry: 1:10, Incubation Time 1 hr at RT.

Comment:

Target Species of Antibody: Xenopus

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: deionized water

Concentration: Lot specific

Buffer: Lyophilized.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for Lamin A/C

Target: Lamin A/C (LMNA)

Alternative Name: LMNA / Lamin A/C

Background: Name/Gene ID: LMNA

Synonyms: LMNA, 70 kDa lamin, CDCD1, CMD1A, EMD2, FPLD, IDC, FPL, FPLD2, Lamin A/C, Lamin, LFP, LMNC, LMN1, LMNL1, HGPS, Prelamin-A/C, PRO1, Lamin A, Lamin A/C-like 1, LGMD1B, CDDC, CMT2B1, LDP1

This antibody detects: LMNA / Lamin A+C

Gene ID: 4000

UniProt: P02545

Pathways: Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus