GPR39 antibody (AA 251-350) (Biotin)

Catalog No. ABIN2174819

The Rabbit Polyclonal anti-GPR39 antibody is suitable to detect GPR39 in samples from Mouse and Rat. It has been validated for ELISA, IHC (p) and IHC (fro).

Quick Overview for GPR39 antibody (AA 251-350) (Biotin) (ABIN2174819)

Target: GPR39 (G Protein-Coupled Receptor 39 (GPR39))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR39 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GPR39 Antibody (Biotin)

Binding Specificity: AA 251-350

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPR39.

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GPR39

Target: GPR39 (G Protein-Coupled Receptor 39 (GPR39))

Alternative Name: GPR39

Background:

Synonyms: G-protein coupled receptor 39, GPR39

Background: Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity).

Gene ID: 2863

UniProt: O43194

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Feeding Behaviour