IFNA1 antibody

Catalog No. ABIN217752

This anti-IFNA1 antibody is a Mouse Monoclonal antibody detecting IFNA1 in WB and ELISA. Suitable for Chicken.

Quick Overview for IFNA1 antibody (ABIN217752)

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Reactivity: Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This IFNA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IFNA1 Antibody

Specificity: Recognizes chicken Interferon alpha (chIFN-alpha). The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent. Does not cross react with IFN beta or IFN gamma and does not neutralize chIFN-alpha.

Purification: Protein G purified

Immunogen: Recombinant chicken Interferon alpha.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, WB

Usage: Western Blot: LS-C44822 detects a band of approximately 19 kD.

Comment:

Target Species of Antibody: Chicken

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for IFNA1

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Alternative Name: IFNA1 / Interferon alpha 1

Background: Name/Gene ID: IFNA1
Family: Interferon

Synonyms: IFNA1, IFN, IFN-alpha 1b, IFNA@, Interferon, alpha 1, LeIF D, Interferon alpha 1b, Interferon alpha-1/13, Interferon alpha-D, Interferon-alpha1, IFL, IFN-ALPHA, IFN-alpha-1/13, IFN-alphaD

Gene ID: 3439

Pathways: JAK-STAT Signaling, Hepatitis C