TNF alpha antibody

Catalog No. ABIN217795

This Mouse Monoclonal antibody specifically detects TNF alpha in ELISA. It exhibits reactivity toward Human.

Quick Overview for TNF alpha antibody (ABIN217795)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNF alpha antibody is un-conjugated

Application: ELISA

Product Details anti-TNF alpha Antibody

Specificity: Recognizes natural and recombinant TNF-alpha. The antibody has an affinity of Kd = 0.5nM, and demonstrates neutralizing activity against human TNF-alpha. Removal of sodium azide is recommended prior to functional assays - XXX recommend the use of EQU003 for this purpose.

No Cross-Reactivity: Mouse (Murine)

Purification: Ion exchange chromatography

Immunogen: Recombinant human TNF-alpha.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF alpha

Background: Name/Gene ID: TNF
Family: TNF

Synonyms: TNF, APC1 protein, Cachectin, DIF, TNF Alpha, Tumor necrosis factor-alpha, TNF-alpha, TNF-a, TNFA, Tumor necrosis factor, TNF, macrophage-derived, TNF, monocyte-derived, TNFSF2

Gene ID: 7124

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome