PCDHB10 antibody (AA 351-450) (Cy5)

Catalog No. ABIN2178251

The Rabbit Polyclonal anti-PCDHB10 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect PCDHB10 in samples from Human and Rat.

Quick Overview for PCDHB10 antibody (AA 351-450) (Cy5) (ABIN2178251)

Target: PCDHB10 (Protocadherin beta 10 (PCDHB10))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB10 antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PCDHB10 Antibody (Cy5)

Binding Specificity: AA 351-450

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDHB10

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PCDHB10

Target: PCDHB10 (Protocadherin beta 10 (PCDHB10))

Alternative Name: Pcdhb10

Background:

Synonyms: OTTHUMP00000160026, PCDBA_HUMAN, PCDH BETA10, PCDH-beta-10, PCDHB10, PCHB10,Protocadherin beta-10, Protocadherin beta-10.

Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated a, b and g, all of which contain multiple tandemly-arranged genes. PCDHB10 (protocadherin b10), also known as PCHB10 or PCDH-b10, is an 800 amino acid protein that is one of 16 proteins in the protocadherin b cluster. Unlike the a and g gene clusters, whose genes are spliced to downstream constant-region exons during transcription, members of the b cluster (such as PCDHB10) do not use constant-region exons to produce mRNAs. As a result, each protocadherin b gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB10 is a single-pass type I membrane protein that contains six cadherin domains.