Complement C4 antibody

Catalog No. ABIN2192171

Product Details anti-Complement C4 Antibody

Target: Complement C4 (C4) (Complement 4 (C4))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Complement C4 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunoassay (IA)

Sterility: 0.2 μm filtered

Application Details

Application Notes: For immuno precipitation and immuno assays, the dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.

Restrictions: For Research Use only

Handling

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Expiry Date: 12 months

Target Details for Complement C4

Target: Complement C4 (C4) (Complement 4 (C4))

Alternative Name: c4 (C4 Products)

Synonyms: C4B1 antibody, C4B12 antibody, C4B2 antibody, C4B3 antibody, C4B5 antibody, C4BD antibody, C4B_2 antibody, C4F antibody, CH antibody, CO4 antibody, CPAMD3 antibody, C4 antibody, C4A2 antibody, C4A3 antibody, C4A4 antibody, C4A6 antibody, C4AD antibody, C4S antibody, CPAMD2 antibody, RG antibody, C4-1 antibody, C4b antibody, C4-2 antibody, Slp antibody, Ss antibody, complement C4B (Chido blood group) antibody, complement C4A (Rodgers blood group) antibody, complement component 4A (Rodgers blood group) antibody, complement 4 antibody, complement component 4A antibody, complement component 4B (Chido blood group) antibody, C4B antibody, C4A antibody, C4a antibody, C4 antibody, C4b antibody

Background: The polyclonal antibody reacts with Rat C4. Rat complement factor C4, formerly known as Gg protein, consists of an alpha-, beta-, and gamma-chain. The classical pathway of complement and the Mannose binding lectin activation pathway converge at C4. C1s, MASP-1 and MASP-2 cleave C4 resulting in the formation of C4a and C4b. The latter can be cleaved to result in C4c and C4d, in which step all functional sites are lost.

Pathways: Complement System