Integrin Alpha2b antibody (PE)

Catalog No. ABIN219563

The Mouse Monoclonal anti-Integrin Alpha2b antibody has been validated for FACS. It is suitable to detect Integrin Alpha2b in samples from Human and Monkey.

Quick Overview for Integrin Alpha2b antibody (PE) (ABIN219563)

Target: Integrin Alpha2b (CD41)

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-Integrin Alpha2b Antibody (PE)

Specificity: Recognizes the human CD41 cell surface antigen, a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb and functions as a receptor for fibrinogen, fibronectin and vWF. It has not been established if clone 3H1299 recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex. Species cross-reactivity: Clone 3H1299 is reported to cross-react with baboon.

Purification: Ion exchange chromatography

Immunogen: Human platelet plasma membrane.

Type of Immunogen: Membrane preparation

Isotype: IgG1

Application Details

Application Notes: Approved: Flo

Usage: Flow Cytometry: Neat. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 1 mL of Sterile 40-50 % glycerol, distilled water.

Concentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.2, 0.1 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: ITGA2B / CD41

Background: Name/Gene ID: ITGA2B
Family: Integrin

Synonyms: ITGA2B, BDPLT2, CD41B, GT, gp2B, Integrin alpha-IIb, ITGAB, GPIIb, HPA3, Platelet-specific antigen BAK, CD41, CD41 antigen, GPalpha IIb, GTA

Gene ID: 3674

UniProt: P08514

Pathways: Integrin Complex