Bcl-2 antibody (AA 41-54) (Biotin)

Catalog No. ABIN2209165

This Mouse Monoclonal antibody specifically detects Bcl-2 in WB, IHC, FACS, IF and IP. It exhibits reactivity toward Human.

Quick Overview for Bcl-2 antibody (AA 41-54) (Biotin) (ABIN2209165)

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Bcl-2 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 100-D5-124

Product Details anti-Bcl-2 Antibody (Biotin)

Binding Specificity: AA 41-54

Sequence: GAAPAPGIFS SQPG

Cross-Reactivity: Human

Cross-Reactivity (Details): Calculated cross reactivity: Hu

Characteristics: Bcl-2 (Apoptosis regulator Bcl-2, B Cell CLL/lymphoma-2) (Biotin)

Purification: Purified by Protein A/G affinity chromatography.

Immunogen: Synthetic peptide corresponding to aa41-54, GAAPAPGIFSSQPG-Cys, from human Bcl-2. Cellular Localization: Outer mitochondrial membranes and endoplasmic reticulum as well as nuclear membranes.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as a liquid in 10 mM PBS. No preservative added. BSA-Free.

Preservative: Without preservative

Storage: -20 °C

Storage Comment: -20°C

Target Details for Bcl-2

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Alternative Name: Bcl-2

Background: Cellular Localization: Outer mitochondrial membranes and endoplasmic reticulum as well as nuclear membranes.

Pathways: MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling