MEK1 antibody (pThr386)

Catalog No. ABIN221148

The Rabbit Polyclonal anti-MEK1 antibody (ABIN221148) specifically detects MEK1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Chicken and Xenopus laevis samples.

Quick Overview for MEK1 antibody (pThr386) (ABIN221148)

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Chicken, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MEK1 Antibody

Binding Specificity: pThr386

Specificity: Specific for the ~45k MEK 1 protein phosphorylated at Thr386. The immunolabeling is completely eliminated by treatment with X-phosphatase

Purification: Immunoaffinity purified

Immunogen: Phosphopeptide corresponding to amino acid residues surrounding the phosphoThr3 of human MEK 1.

Application Details

Application Notes: Approved: WB (1:1000)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 μLof 10 mM HEPES,  pH 7.5, 150 mM sodium chloride, 0.1 mg/mL BSA, 50 % glycerol.

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details for MEK1

Target: MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))

Alternative Name: MAP2K1 / MEK1

Background: Name/Gene ID: MAP2K1
Subfamily: MAP2K
Family: Protein Kinase

Synonyms: MAP2K1, ERK activator kinase 1, MAPK/ERK kinase 1, MAPKK 1, MKK1, PRKMK1, MEK 1, MAP kinase kinase 1, MAPKK1, MEK1

Gene ID: 5604

UniProt: Q02750

Pathways: MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling