Caspase 8 antibody (AA 223-242)

Catalog No. ABIN2219207

The Rabbit Polyclonal anti-Caspase 8 antibody has been validated for WB. It is suitable to detect Caspase 8 in samples from Human.

Quick Overview for Caspase 8 antibody (AA 223-242) (ABIN2219207)

Target: Caspase 8 (CASP8)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Caspase 8 Antibody

Binding Specificity: AA 223-242

Sequence: DKVYQMKSKP RGYCLIINNH

Cross-Reactivity: Human, Rat (Rattus)

Cross-Reactivity (Details): Calculated cross reactivity: Hu Rt

Characteristics: Caspase 8 (Caspase-8, CASP-8, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, FADD-homologous ICE/Ced-3-like Protease, FADD-like ICE, FLICE, ICE-like Apoptotic Protease 5, MORT1-associated Ced-3 Homolog, MACH, MCH5)

Purification: Purified by immunoaffinity chromatography.

Immunogen: Synthetic peptide corresponding to aa223-242, DKVYQMKSKPRGYCLIINNH, from human Caspase-8. Species Sequence Homology: Mouse

Application Details

Application Notes: Optimal working conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 100 μL sterile ddH2O.

Buffer: Supplied as a lyophilized powder in 5 mg BSA, 0.9 mg sodium chloride, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: Caspase 8

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades