CDK7 antibody (C-Term)

Catalog No. ABIN225881

The Mouse Monoclonal anti-CDK7 antibody has been validated for WB, IHC, IP, IF, IHC (fro) and FACS. It is suitable to detect CDK7 in samples from Human and Mouse.

Quick Overview for CDK7 antibody (C-Term) (ABIN225881)

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDK7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)

Product Details anti-CDK7 Antibody

Binding Specificity: C-Term

Specificity: Antigen Recognized Human, mouse in species (tested so far). Recognizes the key cell cycle regulator cdk7, which is essential to activate the cdk2 kinase in G1 phase and the cdc2 kinase in G2/M phase. The antibody is useful for cell cycle analysis, cell proliferation studies and for immunohistochemistry.

Purification: Protein A purified

Immunogen: Recombinant C-terminal 221aa fragment of human wild-type cdk7/CAK (cyclin activating kinase).

Type of Immunogen: Recombinant protein

Isotype: IgG2b

Application Details

Application Notes: Approved: Flo, IF, IHC, IHC-Fr, IP, WB

Usage: Suitable for use in Immunohistochemistry (frozen sections), Immunofluorescence, Immunoprecipitation of active kinase complex, Cell sorting (FACS analysis) and Western Blot. Immunohistochemistry: 1:10-1:20, Incubation Time 1 hr at room temperature.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: deionized water

Concentration: Lot specific

Buffer: Lyophilized.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for CDK7

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Alternative Name: CDK7

Background: Name/Gene ID: CDK7
Subfamily: CDC2/CDK
Family: Protein Kinase

Synonyms: CDK7, 39 kDa protein kinase, CDK-activating kinase, CDK-activating kinase 1, CDKN7, Cell division protein kinase 7, Cyclin-dependent kinase 7, HCAK, Protein kinase, Mpk-7, Serine/threonine kinase stk1, CAK, CAK1, Crk4, Kinase subunit of CAK, MO15, p39 Mo15, p39MO15, STK1

Gene ID: 1022

UniProt: P50613

Pathways: Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase