H2AFX antibody (pSer139)

Catalog No. ABIN2282264

The Mouse Monoclonal anti-H2AFX antibody is suitable to detect H2AFX in samples from Human. It has been validated for WB, IF, IP, ChIP and IC.

Quick Overview for H2AFX antibody (pSer139) (ABIN2282264)

Target: H2AFX (H2A Histone Family, Member X (H2AFX))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This H2AFX antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunochromatography (IC)

Clone: 2T14

Product Details anti-H2AFX Antibody

Binding Specificity: AA 134-142, pSer139

Sequence: C-KATQApSQEY

Cross-Reactivity: Human

Cross-Reactivity (Details): Calculated cross reactivity: Hu

Characteristics: Histone H2A.X, phosphorylated (Ser139) (H2A histone family member X, H2A.FX, H2A/X, H2AFX)

Purification: Purified by Protein G affinity chromatography.

Immunogen: Synthetic peptide (C-KATQA[pS]QEY) corresponding to aa134-142 of human histone H2A.X. (KLH). The immunizing sequence has 8 identical amino acids in yeast and mouse. MW: 17kD

Isotype: IgG1

Application Details

Application Notes: Optimal working conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as a liquid in PBS, pH 7.6, 0.07 % sodium azide and 30 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C (-20°C Glycerol)

Target Details for H2AFX

Target: H2AFX (H2A Histone Family, Member X (H2AFX))

Alternative Name: Histone H2A.X

Pathways: Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus