Integrin Alpha2b antibody

Catalog No. ABIN234635

The Mouse Monoclonal anti-Integrin Alpha2b antibody has been validated for FACS, IFA and IHC (f). It is suitable to detect Integrin Alpha2b in samples from Human.

Quick Overview for Integrin Alpha2b antibody (ABIN234635)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Flow Cytometry (FACS), Indirect Immunofluorescence Assay (IFA), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: P2

Product Details anti-Integrin Alpha2b Antibody

Specificity: Reacts with gpIIb in the intact complex with gpIIIa, but not with IIb or IIIa, separately. Inhibits platelet aggregation induced by thrombin, collagen and ADP. The molecular weight of the recognized complex is 135 kDa/95 kDa.

Characteristics: MAb to CD41 gpIIb IIIa, Monoclonal antibody to CD41 gpIIb IIIa

Purification: Protein A Chromatography. Ascites

Immunogen: Human platelets

Isotype: IgG1

Application Details

Application Notes: Fluorescence microscopy or flow cytometry: 2 µg/5x106 platelets/test Immunohistochemistry: Working dilution: 1:50 - 1:100. Only suitable on frozen sections or cell smears. Not recommended for use in Western blot. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with 1 mL distilled water.

Buffer: Lyophilized from PBS with 1 mg/mL BSA.

Preservative: Without preservative

Handling Advice: Avoid multiple freeze/thaw cycles. The addition of 0.1 % (w/v) sodium azide is recommended for storage of the Reconstituted form for up to one month at 2-8 °C.
Centrifuge product if not completely clear after standing at room temperature.
Prepare working dilution only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized product at 2-8 °C. After reconstitution, aliquot and store at -28 °C.

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: CD41 gpIIb IIIa

Pathways: Integrin Complex