IGF1 antibody

Catalog No. ABIN235696

This Mouse Monoclonal antibody specifically detects IGF1 in ELISA and RIA. It exhibits reactivity toward Human.

Quick Overview for IGF1 antibody (ABIN235696)

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IGF1 antibody is un-conjugated

Application: ELISA, Radioimmunoassay (RIA)

Clone: BM23

Product Details anti-IGF1 Antibody

Specificity: The basic IGF-1-like forms (pI>9.0) showed substantial cross-reactivity, as did rat and mouse sera. Monoclonal antibody BM23 was capable of abolishing the biological activities of IGF-1 in-vitro bioassays for insulin-like, mitogenic and sulphation activities.

Cross-Reactivity (Details): Cross-reactivity: ILGF-1 100 % ILGF-2 0 % Proinsulin 1.0 % MSF 0 % Insulin <0.0 %

Characteristics: MAb to Somatomedin C, Monoclonal antibody to Human Insulin-Like Growth Factor Type I (IGF-1), Somatomedin C, Tissue culture supernatant

Purification: Ion Exchange Chromatography

Immunogen: Purified human IGF-1 conjugated to ovalbumin

Isotype: IgG1

Application Details

Application Notes: Suitable for use in RIA and ELISA. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.09 % Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid multiple freeze/thaw cycles.
Centrifuge product if not completely clear after standing at room temperature.
Prepare working dilution only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Short-term (up to 1 month) store at 2-8 °C. Long term, aliquot and store at -28 °C.

Expiry Date: 1 month

Target Details for IGF1

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Alternative Name: Insulin-Like Growth Factor Type I (IGF-1), Somatomedin C

Pathways: RTK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation