PAPPA antibody
Quick Overview for PAPPA antibody (ABIN236106)
Target
See all PAPPA AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Specific to the proMBP subunit of heterotetrameric PAPP-A (htPAPP-A, PAPP-A/proMBP). Human PAPP-A antigen purified from placental blood is a heterotetrameric complex, consisting of two PAPP-A subunits and two pro-MBP subunits). Human PAPP-A antigen purified from atherosclerotic plaques is homodimeric consisting of 2 PAPP-A subunits.
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Characteristics
- MAb to PAPP-A, Monoclonal antibody to Human Pregnancy Associated Plasma Protein A (PAPP-A)
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Purification
- Protein A Chromatography. Ascites
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Immunogen
- Purified human PAPP-A/proMBP heterotetrameric complex (htPAPP-A)
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Isotype
- IgG2b
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Application Notes
- Detection of human htPAPP-A antigen in immunoassay and immunoprecipitation. Recognizes proMBP subunit in Western blot. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.1 % Sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 2-8 °C.
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- PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
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Alternative Name
- Pregnancy Associated Plasma Protein A (PAPP-A)
Target
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