TNF alpha antibody (AA 115-130)

Catalog No. ABIN2377390

The Mouse Monoclonal anti-TNF alpha antibody is suitable to detect TNF alpha in samples from Human. It has been validated for IHC, FACS, IP and IF.

Quick Overview for TNF alpha antibody (AA 115-130) (ABIN2377390)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNF alpha antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: TNF706-P-T2

Product Details anti-TNF alpha Antibody

Binding Specificity: AA 115-130

Cross-Reactivity: Human

Cross-Reactivity (Details): Calculated cross reactivity: Hu

Characteristics: TNF-alpha (APC1, Cachectin, Differentiation inducing factor (DIF), Macrophage cytotoxic factor (MCF), Necrosin, TNF alpha, TNF Macrophage Derived, TNF Monocyte Derived, TNF Superfamily Member 2, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2, Tumor Necrosis Factor Precursor)

Purification: Purified by Protein A/G affinity chromatography.

Immunogen: Recombinant human TNF-alpha (TNF706), A hexadecapeptide corresponding to aa115-130 of human TNF-alpha, conjugated to thyroglobulin (P/T2). Cellular Localization: Cytoplasmic and extracellular (secreted)

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied as a liquid in 10 mM PBS, 0.05 % BSA, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNF-alpha

Background: Cellular Localization: Cytoplasmic and extracellular (secreted)

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome