PRKAR1B antibody, AI385716 antibody, RIbeta antibody, RGD1563094 antibody, PRKAR1 antibody, zgc:153624 antibody, prkar1 antibody, protein kinase cAMP-dependent type I regulatory subunit beta antibody, protein kinase, cAMP dependent regulatory, type I beta antibody, protein kinase cAMP-dependent type 1 regulatory subunit beta antibody, protein kinase, cAMP-dependent, regulatory, type I, beta antibody, protein kinase, cAMP-dependent, regulatory subunit type I beta S homeolog antibody, PRKAR1B antibody, prkar1b antibody, Prkar1b antibody, prkar1b.S antibody
Background
Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.