GREM1 antibody
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- Target See all GREM1 Antibodies
- GREM1 (Gremlin 1 (GREM1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GREM1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human GREM1
- Isotype
- IgG
- Top Product
- Discover our top product GREM1 Primary Antibody
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- Application Notes
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.3 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Handling Advice
- Avoid freeze / thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- GREM1 (Gremlin 1 (GREM1))
- Alternative Name
- GREM1 (GREM1 Products)
- Synonyms
- grem1 antibody, MGC136702 antibody, zgc:136702 antibody, GREM1 antibody, drm antibody, pig2 antibody, dand2 antibody, ihg-2 antibody, gremlin antibody, Cktsf1b1 antibody, Drm antibody, Grem antibody, ld antibody, gremlin-1 antibody, CKTSF1B1 antibody, DAND2 antibody, DRM antibody, GREMLIN antibody, IHG-2 antibody, cktsf1b1 antibody, gremlin 1a, DAN family BMP antagonist antibody, gremlin 1, DAN family BMP antagonist antibody, gremlin 1 antibody, gremlin 1, DAN family BMP antagonist L homeolog antibody, grem1a antibody, GREM1 antibody, LOC662541 antibody, grem1 antibody, Grem1 antibody, grem1.L antibody
- Background
- This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- Calculated MW: 21 kDa
- Pathways
- Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location
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