STRADB antibody

Catalog No. ABIN2429143

Product Details anti-STRADB Antibody

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRADB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Affinity purification

Immunogen: Recombinant protein of human STRADB

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STRADB

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Alternative Name: STRADB (STRADB Products)

Synonyms: Als2cr2 antibody, RGD1559449 antibody, als2cr2 antibody, MGC82468 antibody, STRADB antibody, ALS2CR2 antibody, AA792893 antibody, B830008M19 antibody, D1Ucla2 antibody, ILPIP antibody, ILPIPA antibody, PRO1038 antibody, Papk antibody, Syradb antibody, CALS-21 antibody, PAPK antibody, STE20-related kinase adaptor beta antibody, STE20-related kinase adaptor beta L homeolog antibody, Stradb antibody, STRADB antibody, stradb.L antibody

Background: This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: Calculated MW: 47/31

Pathways: AMPK Signaling