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SMARCA4 antibody
SMARCA4
Reactivity: Human, Mouse, Rat
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SMARCA4 Antibody
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Target
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SMARCA4
(SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))
Reactivity
All reactivities for SMARCA4 antibodies
Human, Mouse, Rat
Host
All hosts for SMARCA4 antibodies
Rabbit
Clonality
All clonalities for SMARCA4 antibodies
Polyclonal
Conjugate
All conjugates for SMARCA4 antibodies
This SMARCA4 antibody is un-conjugated
Application
All applications for SMARCA4 antibodies
Western Blotting (WB), ELISA
Purification
Affinity purification
Immunogen
Synthetic peptide of human SMARCA4
Isotype
IgG
Top Product
Discover our top product SMARCA4 Primary Antibody
Alternatives
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anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) (AA 1420-1470), (C-Term) antibody
SMARCA4
Reactivity: Human, Mouse, Rat
WB, ELISA, IF, IHC (p), CUT&RUN
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB 1:500-1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.4 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Handling Advice
Avoid freeze / thaw cycles.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for SMARCA4
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Target
SMARCA4
(SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))
Alternative Name
SMARCA4 (SMARCA4 Products )
Synonyms
SMARCA4 antibody, BAF190 antibody, BAF190A antibody, BRG1 antibody, MRD16 antibody, RTPS2 antibody, SNF2 antibody, SNF2L4 antibody, SNF2LB antibody, SWI2 antibody, hSNF2b antibody, brg-1 antibody, Brg1 antibody, HP1-BP72 antibody, SNF2beta antibody, SW1/SNF antibody, b2b692Clo antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 antibody, SMARCA4 antibody, Smarca4 antibody
Background
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Molecular Weight
Calculated MW: 185 kDa
NCBI Accession
NP_003063
Pathways
Intracellular Steroid Hormone Receptor Signaling Pathway , Regulation of Intracellular Steroid Hormone Receptor Signaling , Stem Cell Maintenance
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