RYR1 antibody

Catalog No. ABIN2433723

Product Details anti-RYR1 Antibody

Target: RYR1 (Ryanodine Receptor 1 (Skeletal) (RYR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RYR1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Affinity purification

Immunogen: Synthetic peptide of human RYR1

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RYR1

Target: RYR1 (Ryanodine Receptor 1 (Skeletal) (RYR1))

Alternative Name: RYR1 (RYR1 Products)

Synonyms: ryr1 antibody, RYR1 antibody, alphaRYR antibody, CCO antibody, MHS antibody, MHS1 antibody, RYDR antibody, RYR antibody, RYR-1 antibody, SKRR antibody, Ryr1l antibody, CRC antibody, AI528790 antibody, Ryr antibody, skrr antibody, ryanodine receptor 1 antibody, ryanodine receptor 1 (skeletal) antibody, ryanodine receptor 1a (skeletal) antibody, ryanodine receptor 1, skeletal muscle antibody, RYR1 antibody, ryr1a antibody, Ryr1 antibody

Background: This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described.

Molecular Weight: Calculated MW: 565 kDa

NCBI Accession: NP_000531

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development