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PFKFB1 antibody

PFKFB1 Reactivity: Human, Mouse, Rat ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2434216
  • Target See all PFKFB1 Antibodies
    PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
    Reactivity
    • 36
    • 31
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 50
    • 1
    Rabbit
    Clonality
    • 51
    Polyclonal
    Conjugate
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PFKFB1 antibody is un-conjugated
    Application
    • 43
    • 21
    • 16
    • 13
    • 13
    • 10
    • 3
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human PFKFB1
    Isotype
    IgG
    Top Product
    Discover our top product PFKFB1 Primary Antibody
  • Application Notes
    IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Handling Advice
    Avoid freeze / thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))
    Alternative Name
    PFKFB1 (PFKFB1 Products)
    Synonyms
    zgc:55328 antibody, wu:fi11h10 antibody, PFKFB1 antibody, F6PK antibody, HL2K antibody, PFRX antibody, Pfkfb01 antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 antibody, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 S homeolog antibody, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 antibody, pfkfb1 antibody, PFKFB1 antibody, pfkfb1.S antibody, LOC100475853 antibody, Pfkfb1 antibody
    Background
    This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.
    NCBI Accession
    NP_002616
    Pathways
    Regulation of Carbohydrate Metabolic Process
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