Tyrosine Hydroxylase antibody (full length)

Catalog No. ABIN2443822

This Mouse Monoclonal antibody specifically detects Tyrosine Hydroxylase in IHC, IF and ICC. It exhibits reactivity toward Rat.

Quick Overview for Tyrosine Hydroxylase antibody (full length) (ABIN2443822)

Target: Tyrosine Hydroxylase (TH)

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tyrosine Hydroxylase antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: TOH A1-1

Product Details anti-Tyrosine Hydroxylase Antibody

Binding Specificity: full length

Purpose: Tyrosine Hydroxylase Mouse Monoclonal Antibody (TOH A1.1)

Specificity: The antibody recognizes the full length TOH

Purification: Protein G purified

Immunogen: Full length TOH

Isotype: IgG1

Application Details

Application Notes: IHC 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: If reconstituted with deionized water in 500 μL: IHC 1:100 - 1:250. Optimal dilution has to be determined by the user.

Buffer: Lyophilized protein G purified in PBS pH 7.4

Preservative: Without preservative

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Expiry Date: 24 months

Target Details for Tyrosine Hydroxylase

Target: Tyrosine Hydroxylase (TH)

Alternative Name: Tyrosine Hydroxylase

Background:

Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH, TOH

Tyrosine hydroxylase is the rate-limiting enzyme in the catecholamine synthesis. It is responsible for the hydroxylation of L-tyrosine, which is further converted to give rise to dopamine, norepinephrine and epinephrine.

UniProt: P04177

Pathways: Dopaminergic Neurogenesis, Response to Water Deprivation, Sensory Perception of Sound, Carbohydrate Homeostasis, Feeding Behaviour