KCNV2 antibody

Catalog No. ABIN2458144

Product Details anti-KCNV2 Antibody

Target: KCNV2 (Potassium Channel, Subfamily V, Member 2 (KCNV2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNV2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNV2.

Application Details

Application Notes: KCNV2 antibody can be used for detection of KCNV2 by ELISA at 1:1562500. KCNV2 antibody can be used for detection of KCNV2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KCNV2 antibody at -20 °C.

Target Details for KCNV2

Target: KCNV2 (Potassium Channel, Subfamily V, Member 2 (KCNV2))

Alternative Name: KCNV2 (KCNV2 Products)

Synonyms: KV11.1 antibody, Kv8.2 antibody, RCD3B antibody, potassium voltage-gated channel modifier subfamily V member 2 antibody, potassium channel, subfamily V, member 2 antibody, KCNV2 antibody, Kcnv2 antibody

Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. KCNV2 is strongly expressed in pancreas and has a weaker expression in several other tissues.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues.

Molecular Weight: 62 kDa

Gene ID: 169522

NCBI Accession: NP_598004

UniProt: Q8TDN2