ERCC5 antibody

Catalog No. ABIN2459724

Product Details anti-ERCC5 Antibody

Target: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERCC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ERCC5.

Application Details

Application Notes: ERCC5 antibody can be used for detection of ERCC5 by ELISA at 1:62500. ERCC5 antibody can be used for detection of ERCC5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ERCC5 antibody at -20 °C.

Target Details for ERCC5

Target: ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

Alternative Name: ERCC5 (ERCC5 Products)

Synonyms: COFS3 antibody, ERCM2 antibody, UVDR antibody, XPG antibody, XPGC antibody, cofs3 antibody, ercm2 antibody, uvdr antibody, xpg antibody, xpgc antibody, Xpg antibody, ERCC excision repair 5, endonuclease antibody, excision repair cross-complementation group 5 L homeolog antibody, excision repair cross-complementing rodent repair deficiency, complementation group 5 antibody, ERCC5 antibody, ercc5.L antibody, Ercc5 antibody

Background: Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 133 kDa

Gene ID: 2073

NCBI Accession: NP_000114

UniProt: P28715

Pathways: DNA Damage Repair