CENPP antibody

Catalog No. ABIN2459748

Product Details anti-CENPP Antibody

Target: CENPP (Centromere Protein P (CENPP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CENPP.

Application Details

Application Notes: CENPP antibody can be used for detection of CENPP by ELISA at 1:312500. CENPP antibody can be used for detection of CENPP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CENPP antibody at -20 °C.

Target Details for CENPP

Target: CENPP (Centromere Protein P (CENPP))

Alternative Name: CENPP (CENPP Products)

Synonyms: CENP-P antibody, 1700022C02Rik antibody, 4921518G09Rik antibody, si:ch211-103f16.3 antibody, wu:fb81h12 antibody, zgc:101125 antibody, centromere protein P antibody, CENPP antibody, Cenpp antibody, cenpp antibody

Background: CENPP is the component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. CENPP may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).

Molecular Weight: 33 kDa

Gene ID: 401541

NCBI Accession: NP_001012267

UniProt: Q6IPU0