ACADVL antibody

Catalog No. ABIN2459763

Product Details anti-ACADVL Antibody

Target: ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACADVL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ACADVL.

Application Details

Application Notes: ACADVL antibody can be used for detection of ACADVL by ELISA at 1:312500. ACADVL antibody can be used for detection of ACADVL by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ACADVL antibody at -20 °C.

Target Details for ACADVL

Target: ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))

Alternative Name: ACADVL (ACADVL Products)

Synonyms: ACAD6 antibody, LCACD antibody, VLCAD antibody, vlcad antibody, fb52d04 antibody, wu:fb52d04 antibody, wu:fc75e01 antibody, zgc:64067 antibody, acyl-CoA dehydrogenase very long chain antibody, acyl-Coenzyme A dehydrogenase, very long chain antibody, acyl-CoA dehydrogenase, very long chain antibody, ACADVL antibody, Acadvl antibody, acadvl antibody

Background: ACADVL is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in ACADVL protein reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy.The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 64 kDa

Gene ID: 37

NCBI Accession: NP_001029031

UniProt: P49748

Pathways: ER-Nucleus Signaling, Monocarboxylic Acid Catabolic Process