TMOD3 antibody

Catalog No. ABIN2459847

Product Details anti-TMOD3 Antibody

Target: TMOD3 (Tropomodulin 3 (TMOD3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMOD3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TMOD3.

Application Details

Application Notes: TMOD3 antibody can be used for detection of TMOD3 by ELISA at 1:62500. TMOD3 antibody can be used for detection of TMOD3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TMOD3 antibody at -20 °C.

Target Details for TMOD3

Target: TMOD3 (Tropomodulin 3 (TMOD3))

Alternative Name: TMOD3 (TMOD3 Products)

Synonyms: TMOD3 antibody, tropomodulin-3 antibody, UTMOD antibody, MGC53545 antibody, U-Tmod antibody, tropomodulin 3 antibody, tropomodulin 3 S homeolog antibody, TMOD3 antibody, Tmod3 antibody, tmod3.S antibody, tmod3 antibody

Background: TMOD3 belongs to the tropomodulin family. It blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway.

Molecular Weight: 39 kDa

Gene ID: 29766

NCBI Accession: NP_055362

UniProt: Q9NYL9

Pathways: Regulation of Actin Filament Polymerization