GCFC2 antibody

Catalog No. ABIN2460017

Product Details anti-GCFC2 Antibody

Target: GCFC2 (GC-Rich Sequence DNA-Binding Factor 2 (GCFC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCFC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human C2orf3.

Application Details

Application Notes: C2orf3 antibody can be used for detection of C2orf3 by ELISA at 1:12500. C2orf3 antibody can be used for detection of C2orf3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store C2orf3 antibody at -20 °C.

Target Details for GCFC2

Target: GCFC2 (GC-Rich Sequence DNA-Binding Factor 2 (GCFC2))

Alternative Name: C2orf3 (GCFC2 Products)

Synonyms: C2orf3 antibody, DNABF antibody, GCF antibody, TCF9 antibody, A130099G21 antibody, AW146020 antibody, GCF2 antibody, Tcf9 antibody, C11H2orf3 antibody, RGD1304792 antibody, C17H2orf3 antibody, zgc:171819 antibody, GC-rich sequence DNA-binding factor 2 antibody, GC-rich sequence DNA binding factor 2 antibody, GCFC2 antibody, Gcfc2 antibody, gcfc2 antibody

Background: The first mRNA transcript isolated for C2orf3 gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). C2orf3 belongs to the GCF family. It is a factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene.

Molecular Weight: 89 kDa

Gene ID: 6936

NCBI Accession: NP_003194

UniProt: P16383