TRAF4 antibody

Catalog No. ABIN2460103

Product Details anti-TRAF4 Antibody

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRAF4.

Application Details

Application Notes: TRAF4 antibody can be used for detection of TRAF4 by ELISA at 1:62500. TRAF4 antibody can be used for detection of TRAF4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TRAF4 antibody at -20 °C.

Target Details for TRAF4

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Alternative Name: TRAF4 (TRAF4 Products)

Synonyms: CART1 antibody, MLN62 antibody, RNF83 antibody, A530032M13Rik antibody, msp2 antibody, traf4 antibody, cart1 antibody, mln62 antibody, rnf83 antibody, traf-4 antibody, traf4l antibody, zgc:77418 antibody, TNF receptor associated factor 4 antibody, Tnf receptor associated factor 4 antibody, tnf receptor-associated factor 4b antibody, TNF receptor associated factor 4 L homeolog antibody, tnf receptor-associated factor 4a antibody, TRAF4 antibody, Traf4 antibody, traf4b antibody, traf4.L antibody, traf4a antibody

Background: TRAF4 is a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. It has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD (P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK.This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD (P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 53 kDa

Gene ID: 9618

NCBI Accession: NP_004286

UniProt: Q9BUZ4