MYST2 antibody

Catalog No. ABIN2460592

Product Details anti-MYST2 Antibody

Target: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYST2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MYST2.

Application Details

Application Notes: MYST2 antibody can be used for detection of MYST2 by ELISA at 1:62500. MYST2 antibody can be used for detection of MYST2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MYST2 antibody at -20 °C.

Target Details for MYST2

Target: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Alternative Name: MYST2 (MYST2 Products)

Synonyms: Myst2 antibody, HBO1 antibody, HBOA antibody, MYST2 antibody, ZC2HC7 antibody, Hbo1 antibody, Hboa antibody, lysine acetyltransferase 7 antibody, K(lysine) acetyltransferase 7 antibody, MYST histone acetyltransferase 2 antibody, Kat7 antibody, KAT7 antibody, myst2 antibody

Background: MYST2 belongs to the MYST family, which is characterized by a highly conserved C2HC zinc finger and a putative histone acetyltransferase domain. MYST2 specifically represses AR-mediated transcription. MYST2 is a new AR-interacting protein capable of modulating AR activity. It could play a significant role in regulating AR-dependent genes in normal and prostate cancer cells. The biochemical and genetic interactions of MYST family protein MYST2 with two components of the replication apparatus, MCM2 and ORC1, suggest that MYST2-associated HAT activity may play a direct role in the process of DNA replication. MYST2 is a positive regulatory factor for prereplicative complex assembly.

Molecular Weight: 71 kDa

Gene ID: 11143

NCBI Accession: NP_008998

UniProt: O95251