IVNS1ABP antibody

Catalog No. ABIN2460653

The Rabbit Polyclonal anti-IVNS1ABP antibody has been validated for WB, IHC and ELISA. It is suitable to detect IVNS1ABP in samples from Human and Dog.

Quick Overview for IVNS1ABP antibody (ABIN2460653)

Target: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IVNS1ABP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-IVNS1ABP Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IVNS1ABP.

Application Details

Application Notes: IVNS1ABP antibody can be used for detection of IVNS1ABP by ELISA at 1:312500. IVNS1ABP antibody can be used for detection of IVNS1ABP by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store IVNS1ABP antibody at -20 °C.

Target Details for IVNS1ABP

Target: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Alternative Name: IVNS1ABP

Target Type: Influenza Protein

Background: This gene encodes a protein which interacts with the nonstructural NS1 protein of the influenza A virus. In noninfected cells, affinity-purified antibodies localized this protein in nuclear regions enriched with the spliceosome assembly factor SC35, suggesting an association with the cellular splicing apparatus. In influenza A virus-infected cells, the protein relocalized throughout the nucleoplasm and appeared distinct from the SC35 domains, which suggests that its function may be disturbed or altered.

Molecular Weight: 72 kDa

Gene ID: 10625

NCBI Accession: NP_006460

UniProt: Q9Y6Y0

Pathways: Negative Regulation of intrinsic apoptotic Signaling