T-Box 5 antibody

Catalog No. ABIN2460713

Product Details anti-T-Box 5 Antibody

Target: T-Box 5 (TBX5)

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TBX5.

Application Details

Application Notes: TBX5 antibody can be used for detection of TBX5 by ELISA at 1:62500. TBX5 antibody can be used for detection of TBX5 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TBX5 antibody at -20 °C.

Target Details for T-Box 5

Target: T-Box 5 (TBX5)

Alternative Name: TBX5 (TBX5 Products)

Synonyms: TBX5 antibody, tbx-5 antibody, xtbx-5 antibody, xtbx5 antibody, tbx5 antibody, HOS antibody, tbx5.1 antibody, zTbx5 antibody, zf-tbx5 antibody, T-box 5 antibody, T-box 5 L homeolog antibody, T-box 5a antibody, TBX5 antibody, tbx5 antibody, tbx5.L antibody, Tbx5 antibody, tbx5a antibody

Background: TBX5 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs.

Molecular Weight: 39 kDa

Gene ID: 6910

NCBI Accession: NP_542449

UniProt: Q99593