CLCNKB antibody

Catalog No. ABIN2461076

Product Details anti-CLCNKB Antibody

Target: CLCNKB (Chloride Channel Kb (CLCNKB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCNKB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLCNKB.

Application Details

Application Notes: CLCNKB antibody can be used for detection of CLCNKB by ELISA at 1:312500. CLCNKB antibody can be used for detection of CLCNKB by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CLCNKB antibody at -20 °C.

Target Details for CLCNKB

Target: CLCNKB (Chloride Channel Kb (CLCNKB))

Alternative Name: CLCNKB (CLCNKB Products)

Synonyms: CLCNKA antibody, CLCNKB antibody, DKFZp469N0132 antibody, CLCKB antibody, Clc-Ka antibody, Clck2 antibody, Clcnk1l antibody, ClC-K2L antibody, ClC-K2 antibody, ClC-Kb antibody, ClC-k antibody, clc-kb antibody, clckb antibody, clcnka-A antibody, clk-k2 antibody, x6clck antibody, xCIC-K antibody, xClC-K antibody, zgc:64141 antibody, Clcnkb antibody, chloride voltage-gated channel Kb antibody, chloride channel Kb antibody, chloride channel, voltage-sensitive Kb antibody, chloride channel, voltage-sensitive Kb L homeolog antibody, chloride channel K antibody, chloride channel protein ClC-Ka antibody, chloride channel protein ClC-Kb antibody, CLCNKB antibody, Clcnkb antibody, clcnkb.L antibody, clcnk antibody, LOC100017912 antibody, LOC100400180 antibody, LOC100590605 antibody, LOC100730738 antibody

Background: Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94 % sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.

Molecular Weight: 50 kDa, 75 kDa

Gene ID: 1188

UniProt: Q8WW53