PBX2 antibody

Catalog No. ABIN2461667

Product Details anti-PBX2 Antibody

Target: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PBX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PBX2.

Application Details

Application Notes: PBX2 antibody can be used for detection of PBX2 by ELISA at 1:62500. PBX2 antibody can be used for detection of PBX2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PBX2 antibody at -20 °C.

Target Details for PBX2

Target: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Alternative Name: PBX2 (PBX2 Products)

Synonyms: G17 antibody, HOX12 antibody, PBX2MHC antibody, AU043397 antibody, pbxy antibody, wu:fb73g03 antibody, hox12 antibody, pbx2mhc antibody, PBX2P1 antibody, PBX homeobox 2 antibody, pre B cell leukemia homeobox 2 antibody, pre-B-cell leukemia homeobox 2 antibody, pre-B-cell leukemia homeobox 2 L homeolog antibody, PBX2 antibody, Pbx2 antibody, pbx2 antibody, pbx2.L antibody

Background: PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t (1,19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t (1,19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.

Molecular Weight: 46 kDa

Gene ID: 5089

NCBI Accession: NP_002577

UniProt: P40425

Pathways: Skeletal Muscle Fiber Development