NR2F2 antibody

Catalog No. ABIN2461905

Product Details anti-NR2F2 Antibody

Target: NR2F2 (Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR2F2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR2F2.

Application Details

Application Notes: NR2F2 antibody can be used for detection of NR2F2 by ELISA at 1:312500. NR2F2 antibody can be used for detection of NR2F2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NR2F2 antibody at -20 °C.

Target Details for NR2F2

Target: NR2F2 (Nuclear Receptor Subfamily 2, Group F, Member 2 (NR2F2))

Alternative Name: NR2F2 (NR2F2 Products)

Synonyms: nr2f2 antibody, MGC52954 antibody, ARP1 antibody, COUPTFB antibody, COUPTFII antibody, NF-E3 antibody, NR2F1 antibody, SVP40 antibody, TFCOUP2 antibody, 2700033K02Rik antibody, 9430015G03Rik antibody, ARP-1 antibody, Aporp1 antibody, COUP-TF2 antibody, COUP-TFII antibody, EAR3 antibody, Tcfcoup2 antibody, Tfcoup2 antibody, fc94g08 antibody, svp40 antibody, svp[40] antibody, wu:fc94g08 antibody, nuclear receptor subfamily 2 group F member 2 L homeolog antibody, Nr2f2 protein antibody, nuclear receptor subfamily 2 group F member 2 antibody, nuclear receptor subfamily 2, group F, member 2 antibody, nr2f2.L antibody, nr2f2 antibody, NR2F2 antibody, Nr2f2 antibody

Background: NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation.

Molecular Weight: 45 kDa

Gene ID: 7026

NCBI Accession: NP_066285

UniProt: P24468

Pathways: Steroid Hormone Mediated Signaling Pathway