DTX2 antibody

Catalog No. ABIN2462679

This anti-DTX2 antibody is a Rabbit Polyclonal antibody detecting DTX2 in WB and ELISA. Suitable for Human, Dog and Zebrafish (Danio rerio).

Quick Overview for DTX2 antibody (ABIN2462679)

Target: DTX2 (Deltex Homolog 2 (DTX2))

Reactivity: Human, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTX2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DTX2 Antibody

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DTX2.

Application Details

Application Notes: DTX2 antibody can be used for detection of DTX2 by ELISA at 1:312500. DTX2 antibody can be used for detection of DTX2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DTX2 antibody at -20 °C.

Target Details for DTX2

Target: DTX2 (Deltex Homolog 2 (DTX2))

Alternative Name: DTX2

Background: DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Molecular Weight: 62 kDa, 67 kDa, 67 kDa, 67 kDa, 93 kDa, 26 kDa, 93 kDa, 45 kDa

Gene ID: 113878

NCBI Accession: NP_001096066

UniProt: Q6XM87

Pathways: Notch Signaling