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DTX2 antibody

DTX2 Reactivity: Human, Dog, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN630801
  • Target See all DTX2 Antibodies
    DTX2 (Deltex Homolog 2 (DTX2))
    Reactivity
    • 28
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Dog, Zebrafish (Danio rerio)
    Host
    • 25
    • 2
    • 1
    Rabbit
    Clonality
    • 28
    Polyclonal
    Conjugate
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DTX2 antibody is un-conjugated
    Application
    • 26
    • 13
    • 13
    • 8
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Purification
    Affinity purified
    Immunogen
    DTX2 antibody was raised using a synthetic peptide corresponding to a region with amino acids EDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVLE
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    Discover our top product DTX2 Primary Antibody
  • Application Notes
    WB: 0.25 µg/mL
    Optimal conditions should be determined by the investigator.
    Comment

    DTX2 Blocking Peptide, catalog no. 33R-2305, is also available for use as a blocking control in assays to test for specificity of this DTX2 antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DTX2 antibody in PBS
    Concentration
    Lot specific
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Target
    DTX2 (Deltex Homolog 2 (DTX2))
    Alternative Name
    DTX2 (DTX2 Products)
    Synonyms
    RNF58 antibody, 2610524D08Rik antibody, AA408415 antibody, AU022494 antibody, Deltex2 antibody, dtx2 antibody, deltex E3 ubiquitin ligase 2 antibody, probable E3 ubiquitin-protein ligase DTX2 antibody, deltex 2, E3 ubiquitin ligase antibody, deltex 2, E3 ubiquitin ligase S homeolog antibody, DTX2 antibody, Dtx2 antibody, LOC735784 antibody, LOC747633 antibody, dtx2 antibody, dtx2.S antibody
    Background
    DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
    Molecular Weight
    62 kDa (MW of target protein)
    Pathways
    Notch Signaling
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