DTX2 antibody (AA 1-280)

Catalog No. ABIN7164417

Product Details anti-DTX2 Antibody

Target: DTX2 (Deltex Homolog 2 (DTX2))

Binding Specificity: AA 1-280

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DTX2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Probable E3 ubiquitin-protein ligase DTX2 protein (1-280AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DTX2

Target: DTX2 (Deltex Homolog 2 (DTX2))

Alternative Name: DTX2 (DTX2 Products)

Synonyms: RNF58 antibody, 2610524D08Rik antibody, AA408415 antibody, AU022494 antibody, Deltex2 antibody, dtx2 antibody, deltex E3 ubiquitin ligase 2 antibody, probable E3 ubiquitin-protein ligase DTX2 antibody, deltex 2, E3 ubiquitin ligase antibody, deltex 2, E3 ubiquitin ligase S homeolog antibody, DTX2 antibody, Dtx2 antibody, LOC735784 antibody, LOC747633 antibody, dtx2 antibody, dtx2.S antibody

Background:

Background: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Aliases: Deltex 2 antibody, deltex homolog 2 (Drosophila) antibody, deltex, Drosophila, homolog of, 2 antibody, Deltex2 antibody, DTX2 antibody, DTX2_HUMAN antibody, hDTX2 antibody, Highly similar to hPMSR6 [H.sapiens] antibody, KIAA1528 antibody, Probable E3 ubiquitin-protein ligase DTX2 antibody, Protein deltex 2 antibody, Protein deltex-2 antibody, RING finger protein 58 antibody, RNF58 antibody, Zinc ion binding protein antibody

UniProt: Q86UW9

Pathways: Notch Signaling