M6PR antibody

Catalog No. ABIN2462706

The Rabbit Polyclonal anti-M6PR antibody (ABIN2462706) specifically detects M6PR in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for M6PR antibody (ABIN2462706)

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This M6PR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-M6PR Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human M6PR.

Application Details

Application Notes: M6PR antibody can be used for detection of M6PR by ELISA at 1:312500. M6PR antibody can be used for detection of M6PR by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store M6PR antibody at -20 °C.

Target Details for M6PR

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Alternative Name: M6PR

Background: M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.The protein encoded by this gene is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.

Molecular Weight: 28 kDa

Gene ID: 4074

NCBI Accession: NP_002346

UniProt: P20645