PCDH15 antibody

Catalog No. ABIN2463319

Product Details anti-PCDH15 Antibody

Target: PCDH15 (Protocadherin-15 (PCDH15))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDH15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDH15.

Application Details

Application Notes: PCDH15 antibody can be used for detection of PCDH15 by ELISA at 1:62500. PCDH15 antibody can be used for detection of PCDH15 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCDH15 antibody at -20 °C.

Target Details for PCDH15

Target: PCDH15 (Protocadherin-15 (PCDH15))

Alternative Name: PCDH15 (PCDH15 Products)

Synonyms: CDHR15 antibody, DFNB23 antibody, USH1F antibody, BB078305 antibody, ENSMUSG00000046980 antibody, Gm9815 antibody, Ush1f antibody, av antibody, nmf19 antibody, protocadherin-15 antibody, protocadherin related 15 antibody, protocadherin-15 antibody, protocadherin 15 antibody, PCDH15 antibody, CpipJ_CPIJ005081 antibody, Pcdh15 antibody

Background: PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.

Molecular Weight: 80 kDa

Gene ID: 65217

UniProt: A2A3E5

Pathways: Sensory Perception of Sound