TCEB3 antibody

Catalog No. ABIN2463799

Product Details anti-TCEB3 Antibody

Target: TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCEB3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TCEB3.

Application Details

Application Notes: TCEB3 antibody can be used for detection of TCEB3 by ELISA at 1:62500. TCEB3 antibody can be used for detection of TCEB3 by western blot at 7.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TCEB3 antibody at -20 °C.

Target Details for TCEB3

Target: TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))

Alternative Name: TCEB3 (TCEB3 Products)

Synonyms: CG6755 antibody, Dmel\\CG6755 antibody, Elo-A antibody, dEloA antibody, tceb3a antibody, zgc:56638 antibody, wu:fw66g10 antibody, TCEB3 antibody, 110kDa antibody, AA408125 antibody, Tceb3a antibody, El antibody, EloA antibody, SIII antibody, SIII p110 antibody, TCEB3A antibody, Elongin A antibody, transcription elongation factor B polypeptide 3 antibody, elongin A antibody, calcium binding and coiled-coil domain 1b antibody, elongin A S homeolog antibody, transcription elongation factor B subunit 3 antibody, EloA antibody, LOC413407 antibody, eloa antibody, calcoco1b antibody, ELOA antibody, eloa.S antibody, Eloa antibody, TCEB3 antibody

Background: Elongin A (TCEB3), which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits.This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.

Molecular Weight: 87 kDa

Gene ID: 6924

NCBI Accession: NP_003189

UniProt: Q14241