APOA5 antibody (truncated)

Catalog No. ABIN2464012

Product Details anti-APOA5 Antibody

Target: APOA5 (Apolipoprotein A-V (APOA5))

Binding Specificity: truncated

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This APOA5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Immunogen: Ni-NTA purified truncated recombinant human APOA5 expressed in E. Coli strain BL21 (DE3).

Clone: 4H8H8E2(c)

Isotype: IgG1

Application Details

Application Notes: Western Blot, ELISA.
Dilution:
Western Blot:1:500 - 1,000
ELISA:Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: -20 °C

Storage Comment: Apoa5(bd) monoclonal antibody can be stored at -20 °C, stable for one year.

Target Details for APOA5

Target: APOA5 (Apolipoprotein A-V (APOA5))

Alternative Name: Apoa5 (APOA5 Products)

Synonyms: APOAV antibody, RAP3 antibody, 1300007O05Rik antibody, Apoav antibody, apo-AV antibody, apoA-V antibody, APOA5 antibody, MGC140487 antibody, rap3 antibody, apoav antibody, apoa-v antibody, apolipoprotein A5 antibody, apolipoprotein A-V antibody, apolipoprotein A5 L homeolog antibody, APOA5 antibody, Apoa5 antibody, apoa5.L antibody, apoa5 antibody

Background: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglyc erides, whereas a knock-in model with human ApoA5 produced 50 70 % lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-_ agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.

Gene ID: 116519

UniProt: Q6Q788

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism