BNP antibody

Catalog No. ABIN2464019

Product Details anti-BNP Antibody

Target: BNP (Brain Natriuretic Peptide (BNP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BNP antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Synthetic peptide corresponding to aa (Cys-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser) of human BNP1

Clone: 8D5B4C11

Isotype: IgG1

Application Details

Application Notes: IHC(P):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: -20 °C

Storage Comment: BNP1 monoclonal antibody can be stored at -20 °C, stable for one year.

Target Details for BNP

Target: BNP (Brain Natriuretic Peptide (BNP))

Alternative Name: BNP1 (BNP Products)

Synonyms: bnp antibody, BNP1 antibody, NPPB antibody, BNP antibody, Bnf antibody, AA408272 antibody, B-type natriuretic peptide antibody, natriuretic peptide B antibody, natriuretic peptide type B antibody, nppb antibody, NPPB antibody, Nppb antibody

Background: BNP (brain natriuretic peptide) belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. ANP and BNP act mainly as cardiac hormones, produced primarily by the atrium and ventricle, respectively, while the gene encoding C-type natriuretic peptide is expressed mainly in the brain. BNP circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. It is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. This ring structure shows high homology between different natriuretic.

Gene ID: 4879

UniProt: P16860

Pathways: Hormone Activity