KIT antibody (truncated)

Catalog No. ABIN2464038

This anti-KIT antibody is a Mouse Monoclonal antibody detecting KIT in ELISA. Suitable for Human.

Quick Overview for KIT antibody (truncated) (ABIN2464038)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KIT antibody is un-conjugated

Application: ELISA

Clone: 8D7B4-8D7D4-7H6B2-7H6B12

Product Details anti-KIT Antibody

Binding Specificity: truncated

Purification: Antibody is purified by protein A affinity chromatography.

Immunogen: Ni-NTA purified truncated recombinant C-kit expressed in E. Coli strain BL21 (DE3).

Isotype: IgG1

Application Details

Application Notes: Dilution
ELISA:Propose dilution 1:10,000
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: -20 °C

Storage Comment: C-Kit monoclonal antibody can be stored at -20 °C, stable for one year.

Target Details for KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Alternative Name: CKit

Background: C-kit (CD117,145 kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

Gene ID: 3815

UniProt: P10721

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity