beta 2 Adrenergic Receptor antibody (AA 335-408)

Catalog No. ABIN2467938

The Chicken Polyclonal anti-beta 2 Adrenergic Receptor antibody (ABIN2467938) specifically detects beta 2 Adrenergic Receptor in WB. The antibody is reactive with Human samples.

Quick Overview for beta 2 Adrenergic Receptor antibody (AA 335-408) (ABIN2467938)

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Reactivity: Human

Host: Chicken

Clonality: Polyclonal

Conjugate: This beta 2 Adrenergic Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-beta 2 Adrenergic Receptor Antibody

Binding Specificity: AA 335-408

Purification: Immunoaffinity Purified

Application Details

Application Notes: beta-2 adrenergic receptor antibody can be used for the detection of beta-2 adrenergic receptor by Western Blot.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Preservative: Without preservative

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C/-20 °C

Storage Comment: ADRB2 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Target Details for beta 2 Adrenergic Receptor

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Alternative Name: ADRB2

Background: FUNCTION: beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

DISEASE: Polymorphic forms of ADRB2 could impart some form of nocturnal asthma.

SUBUNIT: Binds SLC9A3R1.

PTM: Phosphorylated by PKA and BARK, mediate homologous desensitization of the receptor. PKA-mediated phosphorylation seems to facilitate phosphorylation by BARK

Molecular Weight: 46.6 kDa (calculated)

Gene ID: 154

NCBI Accession: NP_000015

UniProt: P07550

Pathways: cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation