beta 2 Adrenergic Receptor antibody (AA 335-408)
Quick Overview for beta 2 Adrenergic Receptor antibody (AA 335-408) (ABIN2467938)
Target
See all beta 2 Adrenergic Receptor (ADRB2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 335-408
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Purification
- Immunoaffinity Purified
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Application Notes
- beta-2 adrenergic receptor antibody can be used for the detection of beta-2 adrenergic receptor by Western Blot.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline. No preservatives added.
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Preservative
- Without preservative
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Handling Advice
- As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Storage
- 4 °C/-20 °C
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Storage Comment
- ADRB2 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
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- beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))
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Alternative Name
- ADRB2
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Background
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FUNCTION: beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
DISEASE: Polymorphic forms of ADRB2 could impart some form of nocturnal asthma.
SUBUNIT: Binds SLC9A3R1.
PTM: Phosphorylated by PKA and BARK, mediate homologous desensitization of the receptor. PKA-mediated phosphorylation seems to facilitate phosphorylation by BARK -
Molecular Weight
- 46.6 kDa (calculated)
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Gene ID
- 154
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NCBI Accession
- NP_000015
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UniProt
- P07550
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Pathways
- cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
Target
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