PTPRM antibody (Internal Region)

Catalog No. ABIN2469323

The Rabbit Polyclonal anti-PTPRM antibody is suitable to detect PTPRM in samples from Human, Mouse, Rat, Rabbit, Horse, Hamster and Gibbon. It has been validated for IHC.

Quick Overview for PTPRM antibody (Internal Region) (ABIN2469323)

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Reactivity: Human, Mouse, Rat, Rabbit, Horse, Hamster, Gibbon

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRM antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-PTPRM Antibody

Binding Specificity: Internal Region

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: PTPRM antibody was raised against a peptide located near the internal domain of PTPRM (Human).

Application Details

Application Notes: PTPRM antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 - 10 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: PTPRM antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for PTPRM

Target: PTPRM (Protein Tyrosine Phosphatase, Receptor Type, M (PTPRM))

Alternative Name: PTPRM

Background: PTP mu, a R2A receptor protein tyrosine phosphatase, is composed of an extracellular segment containing a MAM domain, an immunoglobulin domain and four fibronectin type III repeats, a transmembrane segment, and two intracellular protein phosphatase domains. PTP mu has been shown to affect cell-cell aggregation, regulate cardiac myocyte Kv1.5 channel expression, and promote neurite outgrowth of retinal ganglion cells. The human PTP mu gene is localized on chromosome 18pter-q11, a region with frequent abnormalities implicated in human cancer. PTP mu may be important in responses to pathological conditions associated with the loss of cell-cell interactions in the heart.

Gene ID: 5797

UniProt: P28827