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Oxytocin Receptor antibody (C-Term)
OXTR
Reactivity: Human
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Oxytocin Receptor Antibody
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Target
See all Oxytocin Receptor (OXTR) Antibodies
Oxytocin Receptor (OXTR)
Binding Specificity
All epitopes for Oxytocin Receptor antibodies
C-Term
Reactivity
All reactivities for Oxytocin Receptor antibodies
Human
Host
All hosts for Oxytocin Receptor antibodies
Rabbit
Clonality
All clonalities for Oxytocin Receptor antibodies
Polyclonal
Conjugate
All conjugates for Oxytocin Receptor antibodies
This Oxytocin Receptor antibody is un-conjugated
Application
All applications for Oxytocin Receptor antibodies
ELISA, Immunohistochemistry (IHC)
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purification
Immunoaffinity Chromatography
Immunogen
Oxytocin Receptor antibody was raised against a peptide located in the C-Terminal cytoplasmic domain of Oxytocin Receptor (Human).
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Alternatives
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Application Details
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Application Notes
Oxytocin Receptor antibody can be used in immunohistochemistry starting at 8 μg/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS, 0.1 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
As with all antibodies avoid freeze/thaw cycles.
Storage
4 °C/-80 °C
Storage Comment
Oxytocin Receptor antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
Target Details for Oxytocin Receptor
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Target
Oxytocin Receptor (OXTR)
Alternative Name
Oxytocin Receptor (OXTR Products )
Synonyms
OXTR antibody, OT-R antibody, OTR antibody, OTR1 antibody, oxytocin receptor antibody, OXTR antibody, Oxtr antibody
Background
The oxytocin receptor belongs to the vasopressin/oxytocin family of GPCRs because it binds similar cyclic nonapeptide hormones. The oxytocin receptor functions primarily during labor and lactation. There is a dramatic increase in the number of oxytocin receptors just before the onset of labor causing the uterine muscles to become exceedingly sensitive to oxytocin. The activated oxytocin receptor causes an inward membrane current that results in smooth muscle contraction during labor and milk ejection during lactation. This receptor also plays a role in natriuresis, kaliuresis and may have an antistress effect.
Gene ID
5021
UniProt
P30559
Pathways
Myometrial Relaxation and Contraction , Feeding Behaviour
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